Megloc Advance Bolus

Manufacturer/Marketer: Rodec Pharmaceuticals Ltd.
Product Type: Veterinary Oral Analgesic & Anti-inflammatory Bolus
Therapeutic Class: NSAID • Analgesic • Antipyretic • Anti-inflammatory • Proteolytic Enzyme Combination
Target Species: Primarily cattle, buffaloes and other large animals
Pack Size: 1 Bolus. 

Composition / Active Ingredients

Megloc Advance Bolus contains:

Flunixin Meglumine + Serratiopeptidase + Cetirizine Hydrochloride + Magnesium Trisilicate

This is a synergistic combination intended to control pain, inflammation, fever and associated tissue swelling. 

The exact quantitative strength of each ingredient was not available in the reliable Rodec documentation I found, so for the Rayavets catalogue, the mg strength of each component should be copied from the current product pack rather than estimated.

Clinical Description

Megloc Advance is a veterinary anti-inflammatory combination designed for rapid and comprehensive relief from severe painful and inflammatory conditions. Flunixin provides potent NSAID, analgesic and antipyretic activity, while Serratiopeptidase supports reduction of inflammatory swelling. Cetirizine provides antihistaminic support, and Magnesium Trisilicate acts as an antacid component.

Indications / Uses

Rodec specifically identifies Megloc Advance Bolus for supportive treatment of severe mastitis, post-operative conditions, severe pain and inflammation, endometritis, metritis and endotoxemia. Other Rodec-associated product information also positions it for inflammatory conditions associated with respiratory tract infections, genital tract infections and high fever/pyrexia. 

Dosage & Administration

Large Animals: Product listings indicate 1–2 boluses daily, but I could not verify a more specific official Rodec dosing schedule from the accessible company documentation. 

For Rayavets, it is safer to state: Administer orally as directed by the veterinarian. Follow the current pack label for exact dose, frequency and duration.

Key Benefits

Megloc Advance provides rapid relief from severe pain and inflammation, helps control pyrexia, reduces inflammatory swelling and provides supportive anti-inflammatory management in severe mastitis, metritis, endometritis, endotoxemia and post-operative conditions. Rodec describes it as a synergistic combination for quick and complete recovery from severe painful and inflammatory conditions. 

Precautions

Use only under veterinary supervision. As the formulation contains an NSAID, use cautiously in dehydrated animals and animals with renal, hepatic or gastrointestinal disease. Avoid simultaneous administration with other NSAIDs or corticosteroids unless specifically directed by a veterinarian.

Possible Adverse Effects

NSAID-containing products may occasionally cause gastrointestinal irritation, reduced appetite, vomiting/diarrhoea or renal effects, particularly with excessive dosing or use in dehydrated animals. Hypersensitivity reactions are also possible.

Storage

Store in a cool, dry place, protected from direct sunlight, heat and moisture. 

Withdrawal Period

I could not verify an authoritative milk or meat withdrawal period specifically for Megloc Advance Bolus. For food-producing animals, use the withdrawal period printed on the current Rodec pack or prescribed by the veterinarian rather than publishing an estimated value.

Important Warning

For veterinary use only. Megloc Advance controls pain, fever and inflammation but does not replace appropriate antimicrobial or other specific therapy when mastitis, metritis, respiratory infection or another bacterial disease is present.

Rayavets Short Description

Megloc Advance Bolus by Rodec Pharmaceuticals Ltd. is a veterinary analgesic and anti-inflammatory combination containing Flunixin Meglumine + Serratiopeptidase + Cetirizine HCl + Magnesium Trisilicate. It provides rapid relief from severe pain, inflammation and fever and is used as supportive treatment in severe mastitis, endometritis, metritis, endotoxemia and post-operative inflammatory conditions. Use orally as directed by a veterinarian.