CALDEE-12® Injection 30 ML

Manufacturer/Marketer: Vetoquinol India Animal Health Pvt. Ltd.
Product Type: Veterinary Injectable Calcium & Vitamin Preparation
Therapeutic Category: Calcium Supplement / Anti-Hypocalcaemic / Vitamin D3 & B12 Support
Target Species: Cows, Buffaloes, Sheep & Goats
Presentation: 30 mL vial
Route: Intramuscular (IM) only
Prescription Status: Veterinary Medicine – use under veterinary supervision. Vetoquinol’s product manual confirms the formulation, indications, dosing and 30 mL presentation. 

Composition

Each 1 mL contains:

• Calcium Levulinate IP – 76.4 mg, equivalent to 10 mg Ionic Calcium
• Cholecalciferol (Vitamin D3) IP – 5,000 IU
• Cyanocobalamin (Vitamin B12) IP – 50 mcg
• Benzyl Alcohol BP – 1.5% w/v, as preservative
• Water for Injection BP – q.s. 

The formulation combines readily available calcium with Vitamin D3, which supports calcium metabolism, and Vitamin B12, which contributes to normal cellular and energy metabolism.

Clinical Description

CALDEE-12 Injection is an injectable calcium, Vitamin D3 and Vitamin B12 preparation formulated for livestock.

According to Vetoquinol's product information, it is intended for the prevention and treatment of hypocalcaemia in cows and buffaloes, particularly during the pre-parturition and post-parturition periods. It is also recommended as a parenteral tonic in animals suffering from debility and weakness. 

Calcium is essential for normal neuromuscular activity, skeletal health and numerous metabolic processes. Vitamin D3 supports calcium utilization, while Vitamin B12 provides additional metabolic and nutritional support.

Indications / Recommended Uses

CALDEE-12 is recommended for:

• Prevention and treatment of hypocalcaemia
• Calcium support during the pre-parturition period
• Calcium support during the post-parturition period
• Nutritional support in weak and debilitated animals
• Parenteral support for improving general health and vitality
• Supporting normal calcium metabolism
• Vitamin D3 and B12 supplementation where clinically appropriate. 

Dosage & Administration

Cows & Buffaloes: 10–12 mL, intramuscularly, three times a week for 1–2 weeks.

Sheep & Goats: 2–3 mL, intramuscularly, three times a week for 1–2 weeks.

Route: IM only, or as directed by the veterinarian. 

Use sterile injection equipment and appropriate aseptic technique. The treatment schedule may be modified by the veterinarian according to the animal's clinical condition and calcium status.

Key Benefits

CALDEE-12 provides combined calcium and vitamin support that may help:

• Prevent and manage hypocalcaemia
• Support cows and buffaloes around parturition
• Provide ionic calcium supplementation
• Support normal calcium utilization through Vitamin D3
• Provide metabolic support through Vitamin B12
• Support animals experiencing weakness and debility
• Improve general nutritional and metabolic support during periods of increased physiological demand. 

Contraindications & Precautions

Do not administer to animals with known hypersensitivity to any component of the formulation.

Use cautiously in animals with disorders associated with abnormally high blood calcium levels or impaired calcium metabolism.

Avoid unnecessary concurrent administration of high-dose calcium or Vitamin D preparations unless specifically recommended by a veterinarian.

Administer by the intramuscular route only according to the manufacturer's listed directions. 

Withdrawal Period

A specific milk or meat withdrawal period is not provided in the Vetoquinol product-manual entry reviewed for CALDEE-12. 

For food-producing animals, follow the current product label/pack insert and the Registered Veterinary Practitioner's instructions regarding any applicable withdrawal requirements.

Possible Adverse Effects

CALDEE-12 is generally expected to be well tolerated when administered at the recommended dose.

Possible reactions associated with injectable preparations can include:

• Temporary pain or irritation at the injection site
• Local swelling
• Rare hypersensitivity reactions

Excessive calcium or Vitamin D administration should be avoided because inappropriate supplementation can disturb normal calcium metabolism.

Storage

Store according to the instructions printed on the current manufacturer-approved label.

Keep the vial protected from direct sunlight, excessive heat and contamination.

Keep out of reach of children.

Important Warning

FOR ANIMAL TREATMENT ONLY. NOT FOR HUMAN USE.

FOR INTRAMUSCULAR USE ONLY.

Administer according to the recommended dose or under the direction of a Registered Veterinary Practitioner.

Do not indiscriminately combine with other high-dose calcium or Vitamin D preparations.

Rayavets Short Description

CALDEE-12 Injection 30 ML by Vetoquinol India Animal Health Pvt. Ltd. is a veterinary injectable calcium and vitamin preparation containing, per mL, Calcium Levulinate 76.4 mg (equivalent to Ionic Calcium 10 mg) + Vitamin D3 5,000 IU + Vitamin B12 50 mcg. It is indicated for the prevention and treatment of hypocalcaemia in cows and buffaloes, particularly during pre- and post-parturition periods, and as a parenteral tonic for debility and weakness. The recommended IM dose is 10–12 mL for cows and buffaloes and 2–3 mL for sheep and goats, three times weekly for 1–2 weeks, or as directed by a veterinarian. Available in a 30 mL vial. For animal treatment only.